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单词 migalastat
释义

migalastat

English

Noun

migalastat (uncountable)

  1. (medicine) A drug used to treat Fabry disease
    • 2015 August 8, “Oral Migalastat HCl Leads to Greater Systemic Exposure and Tissue Levels of Active α-Galactosidase A in Fabry Patients when Co-Administered with Infused Agalsidase”, in PLOS ONE, DOI:10.1371/journal.pone.0134341:
      Based on preclinical data, migalastat HCl in combination with agalsidase is expected to result in the pharmacokinetic (PK) enhancement of agalsidase in plasma by increasing the systemic exposure of active agalsidase, thereby leading to increased cellular levels in disease-relevant tissues.
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