goitrogen

English

Etymology

Coined some time between 1945 and 1950, from goitre +‎ -o- +‎ -gen.[1][2]

Pronunciation

IPA^(key): /ˈɡɔɪtɹədʒən/, /-ˌdʒɛn/

Noun

goitrogen (plural goitrogens)

Any agent that causes goiter, such as thiouracil.
- "We have previously shown that treating rats with the reversible goitrogen 6-propyl-2-thiouracil (PTU) from birth to Day 25 increases testis size and sperm production in adulthood by up to 80% and 140%, respectively."[3]
- "These results suggest that excess iodine induces thyroid involution in goitrogen-treated rats at least partially by apoptosis."[4]

Derived terms

goitrogenic

References

Goitrogen in Dictionary.com
Goitrogen in Merriam-Webster
P. S. Cooke, J. Porcelli, R. A. Hess. Induction of increased testis growth and sperm production in adult rats by neonatal administration of the goitrogen propylthiouracil (PTU): the critical period. Biology of Reproduction. January 1992;46(1):146-54.
[R. B. Burikhanov and S. Matsuzaki. Excess iodine induces apoptosis in the thyroid of goitrogen-pretreated rats in vivo. Thyroid. February 2000;10(2):123-9.]

[1] Goitrogen in Dictionary.com

[2] Goitrogen in Merriam-Webster

[3] P. S. Cooke, J. Porcelli, R. A. Hess. Induction of increased testis growth and sperm production in adult rats by neonatal administration of the goitrogen propylthiouracil (PTU): the critical period. Biology of Reproduction. January 1992;46(1):146-54.

[4] [R. B. Burikhanov and S. Matsuzaki. Excess iodine induces apoptosis in the thyroid of goitrogen-pretreated rats in vivo. Thyroid. February 2000;10(2):123-9.]

单词	goitrogen
释义	goitrogen English Etymology Coined some time between 1945 and 1950, from goitre +‎ -o- +‎ -gen.[1][2] Pronunciation IPA^(key): /ˈɡɔɪtɹədʒən/, /-ˌdʒɛn/ Noun goitrogen (plural goitrogens) Any agent that causes goiter, such as thiouracil. "We have previously shown that treating rats with the reversible goitrogen 6-propyl-2-thiouracil (PTU) from birth to Day 25 increases testis size and sperm production in adulthood by up to 80% and 140%, respectively."[3] "These results suggest that excess iodine induces thyroid involution in goitrogen-treated rats at least partially by apoptosis."[4] Derived terms goitrogenic References Goitrogen in Dictionary.com Goitrogen in Merriam-Webster P. S. Cooke, J. Porcelli, R. A. Hess. Induction of increased testis growth and sperm production in adult rats by neonatal administration of the goitrogen propylthiouracil (PTU): the critical period. Biology of Reproduction. January 1992;46(1):146-54. [R. B. Burikhanov and S. Matsuzaki. Excess iodine induces apoptosis in the thyroid of goitrogen-pretreated rats in vivo. Thyroid. February 2000;10(2):123-9.]
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