chimeric antigen receptor
English
Noun
chimeric antigen receptor (plural chimeric antigen receptors)
- (immunology) A receptor protein engineered to give T cells the (new) ability to attach to a specific target protein.
- Synonyms: CAR, chimeric immunoreceptor, chimeric T cell receptor, artificial T cell receptor
- 2014, Connie Duong, Generation of Novel Chimeric Antigen Receptors to Enhance the Specificity and Activity of T Cells for the Adoptive Immunotherapy for Cancer, University of Melbourne.
- 2020, Mumtaz Yaseen Balkhi, Basics of Chimeric Antigen Receptor (CAR) Immunotherapy, Elsevier (Academic Press).
- 2021, Stela Petkova, Targeting and Elimination of T Cell Subpopulations by Chimeric Antigen Receptor-modified T Cells, Georg-August-Universität Göttingen.
Usage notes
Typically used once to introduce the term and subsequently abbreviated as CAR.
Derived terms
- CAR therapy
- CAR T cell
- chimeric antigen receptor T cell
Translations
type of engineered receptor protein
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