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单词 acedapsone
释义

acedapsone

English

Etymology

Blend of acetate + dapsone

Noun

acedapsone (uncountable)

  1. (pharmacology) An antimicrobial drug that is used to treat leprosy.
    • 1971 September 4, The Lancet, volume 2, number 7723, page 525:
      We report here the successful use of a new repository sulphone, acedapsone, in a field trial in Micronesia, both for the treatment of active leprosy cases and for the prevention of leprosy in an exposed, highly susceptible population.
    • 2010, Roger G. Finch, Antibiotic and Chemotherapy, page 479:
      In the 1960s and 1970s chemoprophylaxis with dapsone and acedapsone was investigated.
    • 2011, R. M. Pinder, “Recent advances in the chemotherapy of malaria”, in Progress in Medicinal Chemistry, volume 8:
      The more intense effect arises, of course, from the relatively facile non-enzymatic hydrolysis of these compounds as opposed to the enzyme-dependent hydrolysis of acedapsone.

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