vorapaxar

English

vorapaxar (uncountable)

A thrombin receptor used to treat patients with a history of myocardial infarction or with peripheral arterial disease.
- 2015 December 3, “Identification and Characterization of Novel Variations in Platelet G-Protein Coupled Receptor (GPCR) Genes in Patients Historically Diagnosed with Type 1 von Willebrand Disease”, in PLOS ONE‎, DOI:10.1371/journal.pone.0143913:
  Crystallographic analysis of this region of the receptor has shown it to be involved in binding to the PAR1 antagonist vorapaxar, which binds to PAR1 to inhibit receptor activation by its tethered ligand.

单词	vorapaxar
释义	vorapaxar English Noun vorapaxar (uncountable) A thrombin receptor used to treat patients with a history of myocardial infarction or with peripheral arterial disease. 2015 December 3, “Identification and Characterization of Novel Variations in Platelet G-Protein Coupled Receptor (GPCR) Genes in Patients Historically Diagnosed with Type 1 von Willebrand Disease”, in PLOS ONE‎, DOI:10.1371/journal.pone.0143913: Crystallographic analysis of this region of the receptor has shown it to be involved in binding to the PAR1 antagonist vorapaxar, which binds to PAR1 to inhibit receptor activation by its tethered ligand.
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