auristatin

English

auristatin (plural auristatins)

Any of a family of particular antineoplastic agents
- 2015 July 11, “Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy”, in PLOS ONE‎, DOI:10.1371/journal.pone.0132282:
  Here, we examine the stability of a non-cleavable Amino-PEG6-based linker bearing the monomethyl auristatin D (MMAD) payload site-specifically conjugated at multiple positions on an antibody.

单词	auristatin
释义	auristatin English Noun auristatin (plural auristatins) Any of a family of particular antineoplastic agents 2015 July 11, “Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy”, in PLOS ONE‎, DOI:10.1371/journal.pone.0132282: Here, we examine the stability of a non-cleavable Amino-PEG6-based linker bearing the monomethyl auristatin D (MMAD) payload site-specifically conjugated at multiple positions on an antibody.
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