polypharmacology

polypharmacology

English

Etymology

poly- +‎ pharmacology

Noun

polypharmacology (plural polypharmacologies)

1. The presence of multiple pharmacologies (targets, modes of action etc) in a single drug
   • 2015 July 16, “Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays”, in PLOS ONE‎, DOI:10.1371/journal.pone.0130796:

     While several classes of kinase inhibitors are highly selective (MEK, covalent modifying kinase inhibitors) many possess a vast polypharmacology across the kinome target-scape.