perturbagen

English

perturb +‎ -gen

perturbagen (plural perturbagens)

A substance (typically a peptide) designed to disrupt intracellular processes, providing information about the operation of pathways and networks within a cell.
- 2015 July 9, Maja Temerinac-Ott, Armaghan W Naik, Robert F Murphy, “Deciding when to stop: efficient experimentation to learn to predict drug-target interactions”, in BMC Bioinformatics‎, volume 16, DOI:10.1186/s12859-015-0650-9:
  To address this problem, we have previously proposed a parametrization of perturbagen-target systems in which we characterize each system by its responsiveness (the probability that a perturbagen has an effect on a target) and its uniqueness (the probability that a perturbagen or target is different from others) [ 18 ].

单词	perturbagen
释义	perturbagen English Etymology perturb +‎ -gen Noun perturbagen (plural perturbagens) A substance (typically a peptide) designed to disrupt intracellular processes, providing information about the operation of pathways and networks within a cell. 2015 July 9, Maja Temerinac-Ott, Armaghan W Naik, Robert F Murphy, “Deciding when to stop: efficient experimentation to learn to predict drug-target interactions”, in BMC Bioinformatics‎, volume 16, DOI:10.1186/s12859-015-0650-9: To address this problem, we have previously proposed a parametrization of perturbagen-target systems in which we characterize each system by its responsiveness (the probability that a perturbagen has an effect on a target) and its uniqueness (the probability that a perturbagen or target is different from others) [ 18 ].
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