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单词 antitubulin
释义

antitubulin

English

Etymology

anti- + tubulin

Adjective

antitubulin (not comparable)

  1. Inhibiting the action of tubulin.
    • 2016 January 28, “MPT0B169, a New Antitubulin Agent, Inhibits Bcr-Abl Expression and Induces Mitochondrion-Mediated Apoptosis in Nonresistant and Imatinib-Resistant Chronic Myeloid Leukemia Cells”, in PLOS ONE, DOI:10.1371/journal.pone.0148093:
      Clinical resistance to the Bcr-Abl inhibitor imatinib is a critical problem in treating CML. This study investigated the antitumor effect and mechanism of MPT0B169, a new antitubulin agent, in K562 CML cells and their derived imatinib-resistant cells, IMR2 and IMR3.

Noun

antitubulin (plural antitubulins)

  1. Any agent that inhibits the action of tubulin.
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