antitubulin
English
Etymology
anti- + tubulin
Adjective
antitubulin (not comparable)
- Inhibiting the action of tubulin.
- 2016 January 28, “MPT0B169, a New Antitubulin Agent, Inhibits Bcr-Abl Expression and Induces Mitochondrion-Mediated Apoptosis in Nonresistant and Imatinib-Resistant Chronic Myeloid Leukemia Cells”, in PLOS ONE, DOI: :
- Clinical resistance to the Bcr-Abl inhibitor imatinib is a critical problem in treating CML. This study investigated the antitumor effect and mechanism of MPT0B169, a new antitubulin agent, in K562 CML cells and their derived imatinib-resistant cells, IMR2 and IMR3.
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Noun
antitubulin (plural antitubulins)
- Any agent that inhibits the action of tubulin.