myristylate

myristylate

English

Etymology

myristyl +‎ -ate

Verb

myristylate (third-person singular simple present myristylates, present participle myristylating, simple past and past participle myristylated)

1. To undergo myristoylation
   • 2000 January 14, Minoru Tateno et al., “Regulation of JNK by Src During Drosophila Development”, in Science‎, volume 287, number 5451, DOI:10.1126/science.287.5451.324, pages 324-327:

     Src42A myri has a point mutation in codon 2, which causes an amino acid substitution from Gly 2 to Asp. Gly 2 is conserved in all members of the Src family and must be myristylated for localization of Src to the cellular membrane in mammals (10 ).

   • 1997 December 19, Tony Pawson & John D. Scott, “Signaling Through Scaffold, Anchoring, and Adaptor Proteins”, in Science‎, volume 278, number 5346, DOI:10.1126/science.278.5346.2075, pages 2075-2080:

     Similarly, FRS2, which is myristylated and has a potential PTB domain, is specifically phosphorylated by receptors for fibroblast growth factor (FGF) and nerve growth factor (NGF) (39 ).