multichaperone

English

multi- +‎ chaperone

multichaperone (plural multichaperones)

(biochemistry) A chaperone consisting of multiple proteins
- 2015 September 29, “The Inhibition of Heat Shock Protein 90 Facilitates the Degradation of Poly-Alanine Expanded Poly (A) Binding Protein Nuclear 1 via the Carboxyl Terminus of Heat Shock Protein 70-Interacting Protein”, in PLOS ONE‎, DOI:10.1371/journal.pone.0138936:
  The complex containing Cdc37 and p23 is thought to be the primary stable form, and the HSP70- and HOP-associated complex is another proteasome-targeting form that induces ubiquitin-proteasome degradation [45, 46 ]. 17-AAG is an ansamycin antibiotic that binds to HSP90 and inhibits the formation of the stabilized HSP90-client protein complex, resulting in the accumulation of the proteasome-targeting HSP90-based multichaperone.

单词	multichaperone
释义	multichaperone English Etymology multi- +‎ chaperone Noun multichaperone (plural multichaperones) (biochemistry) A chaperone consisting of multiple proteins 2015 September 29, “The Inhibition of Heat Shock Protein 90 Facilitates the Degradation of Poly-Alanine Expanded Poly (A) Binding Protein Nuclear 1 via the Carboxyl Terminus of Heat Shock Protein 70-Interacting Protein”, in PLOS ONE‎, DOI:10.1371/journal.pone.0138936: The complex containing Cdc37 and p23 is thought to be the primary stable form, and the HSP70- and HOP-associated complex is another proteasome-targeting form that induces ubiquitin-proteasome degradation [45, 46 ]. 17-AAG is an ansamycin antibiotic that binds to HSP90 and inhibits the formation of the stabilized HSP90-client protein complex, resulting in the accumulation of the proteasome-targeting HSP90-based multichaperone.
随便看	автоколонной автоколонною автоколонну автоколонны автоколоно автокольца автокольцам автокольцами автокольцах автокольце автокольцо автокольцом автокольцу автокран автокрана автокранаар автокранаас автокранам автокранами автокранах автокрангүй автокранд автокране автокранов автокраном