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单词 monoagent
释义

monoagent

English

Etymology

mono- + agent

Noun

monoagent (plural monoagents)

  1. (medicine) Any chemotherapeutic agent that works alone
    • 2015 November 19, “First-In-Class Small Molecule ONC201 Induces DR5 and Cell Death in Tumor but Not Normal Cells to Provide a Wide Therapeutic Index as an Anti-Cancer Agent”, in PLOS ONE, DOI:10.1371/journal.pone.0143082:
      ONC201 is a stable, orally active, blood brain barrier-penetrable compound that has demonstrated p53-independent anti-cancer activity as a monoagent and a combination in several preclinical models that include glioblastoma, breast cancer, colon cancer, lung cancer, lymphoma, and other tumors [1, 10, 11 ].
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