misdifferentiate
English
Etymology
mis- + differentiate
Verb
misdifferentiate (third-person singular simple present misdifferentiates, present participle misdifferentiating, simple past and past participle misdifferentiated)
- To fail to differentiate correctly.
- 2008, Charles J. Epstein, Robert P. Erickson, Anthony Joseph Wynshaw-Boris, Inborn Errors of Development, page 705:
- In the absence of Mxxl, cranial neural crest-derived mesenchyme consequently fails to proliferate and misdifferentiates (Han et al., 2003a).
- 2013, Theodoulakis Christofi & Yiorgos Apidianakis, “Drosophila and the Hallmarks of Cancer”, in Andreas Vilcinskas, editor, Yellow Biotechnology I: Insect Biotechnologie in Drug Discovery and Preclinical Research, page 100:
- Sumoylation-deficient Drosophila lesswright mutants have been shown to induce overproduction of hemocytes and form melanotic tumors whereas Ubc9 mutations activate progenitors to misdifferentiate, become hyperplastic, and develop microtumors [172, 173].
- 2020, Ken-Ichi Furakawa, Shunfu Chin, Toru Asari, Kanichiro Wada, Gentaro Kumagai, & Yasuyuki Ishibashi, “Ectopic Ossification of Human Spinal Ligaments Caused by Mesenchymal Stem Cell Abnormalities”, in Atsushi Okawa, Morio Matsumoto, Motoki Iwasaki, editor, OPLL: Ossification of the Posterior Longitudinal Ligament, page 47:
- Mesenchymal stem cells of patients with ossification are thought to misdifferentiate into osteoblasts instead of target ligament cells because they have high osteogenic ability.