anfibatide

English

anfibatide (uncountable)

(pharmacology) An antithrombotic agent binding to the GPIbα subunit of the glycoprotein Ib-IX-V complex, purified from the venom of the sharp-nosed viper (Deinagkistrodon acutus).
- 2022 June 10, Oliveira, A.L., Viegas, M.F., da Silva, S.L. et al., “The chemistry of snake venom and its medicinal potential”, in Nature Reviews Chemistry‎, volume 6, DOI:10.1038/s41570-022-00393-7, page 462:
  Anfibatide is an anticoagulant C-type lectin-like protein purified from the venom of the sharp-nosed viper (Deinagkistrodon acutus). […] The anticoagulant activity of anfibatide is due to its strong binding to human platelet glycoprotein Ib α-chain (GPIbα), which inhibits the binding of GPIbα with von Willebrand factor (VWF) and thrombin^124,125 (Fig. 6a).

单词	anfibatide
释义	anfibatide English Noun anfibatide (uncountable) (pharmacology) An antithrombotic agent binding to the GPIbα subunit of the glycoprotein Ib-IX-V complex, purified from the venom of the sharp-nosed viper (Deinagkistrodon acutus). 2022 June 10, Oliveira, A.L., Viegas, M.F., da Silva, S.L. et al., “The chemistry of snake venom and its medicinal potential”, in Nature Reviews Chemistry‎, volume 6, DOI:10.1038/s41570-022-00393-7, page 462: Anfibatide is an anticoagulant C-type lectin-like protein purified from the venom of the sharp-nosed viper (Deinagkistrodon acutus). […] The anticoagulant activity of anfibatide is due to its strong binding to human platelet glycoprotein Ib α-chain (GPIbα), which inhibits the binding of GPIbα with von Willebrand factor (VWF) and thrombin^124,125 (Fig. 6a).
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