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单词 mesothelin
释义

mesothelin

English

Etymology

mesothelial + -in

Noun

mesothelin (uncountable)

  1. A protein found in mesothelial cells and overexpressed in several human tumors.
    • 2015 July 15, “IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas”, in PLOS ONE, DOI:10.1371/journal.pone.0133152:
      CAR T cells targeting vascular endothelial growth factor receptor 2 (VEGFR2), epidermal growth factor receptor variant III (EGFRvIII), and mesothelin are being tested in patients with glioblastoma, pancreatic, ovarian and mesothelioma cancers.
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