ibrutinib
English
Noun
ibrutinib (uncountable)
- A targeted covalent inhibitor of Bruton's tyrosine kinase and hence used in treating B cell malignancies.
- 2015 May 22, Georg Lenz, Martin Dreyling, “Insights into the Molecular Pathogenesis of Activated B-Cell-like Diffuse Large B-Cell Lymphoma and Its Therapeutic Implications”, in Cancers, volume 7, DOI: :
- A recent high-throughput screen identified various compounds such as PI3K or BCL2 inhibitors that can be combined favorably with ibrutinib.
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Synonyms
- PCI-32765
- (brandname) Imbruvica