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单词 ibrutinib
释义

ibrutinib

English

Noun

ibrutinib (uncountable)

  1. A targeted covalent inhibitor of Bruton's tyrosine kinase and hence used in treating B cell malignancies.
    • 2015 May 22, Georg Lenz, Martin Dreyling, “Insights into the Molecular Pathogenesis of Activated B-Cell-like Diffuse Large B-Cell Lymphoma and Its Therapeutic Implications”, in Cancers, volume 7, DOI:10.3390/cancers7020812:
      A recent high-throughput screen identified various compounds such as PI3K or BCL2 inhibitors that can be combined favorably with ibrutinib.

Synonyms

  • PCI-32765
  • (brandname) Imbruvica
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