frameshift

English

Etymology

frame +‎ shift

Noun

frameshift (plural frameshifts)

frameshift mutation

Verb

frameshift (third-person singular simple present frameshifts, present participle frameshifting, simple past and past participle frameshifted)

To use a starting point for translating a series of nucleotides that is off by an amount not divisible by three, resulting in an entirely distinct set of codons.
- 2003, Jacques Lapointe & ‎Lea Brakier-Gigras, Translation Mechanisms, →ISBN, page 354:
  Commonly, there are stimulatory signals in mRNA distinct from the shift site that greatly increase the level of frameshifting at the shift site.
- 2004, DNA and Cell Biology - Volume 23, page 702:
  Considering these costs, it seems likely that mechanisms may exist to stop frameshifted translation as soon as possible, depending on the frequency of occurrence.
- 2006, De-Shuang Huang & ‎George William Irwin, Computational Intelligence and Bioinformatics, →ISBN:
  Ribosomal frameshifting at a particular site can yield two protein products from one coding sequence or one protein product from two overlapping open reading frames.

单词	frameshift
释义	frameshift English Etymology frame +‎ shift Noun frameshift (plural frameshifts) frameshift mutation Verb frameshift (third-person singular simple present frameshifts, present participle frameshifting, simple past and past participle frameshifted) To use a starting point for translating a series of nucleotides that is off by an amount not divisible by three, resulting in an entirely distinct set of codons. 2003, Jacques Lapointe & ‎Lea Brakier-Gigras, Translation Mechanisms, →ISBN, page 354: Commonly, there are stimulatory signals in mRNA distinct from the shift site that greatly increase the level of frameshifting at the shift site. 2004, DNA and Cell Biology - Volume 23, page 702: Considering these costs, it seems likely that mechanisms may exist to stop frameshifted translation as soon as possible, depending on the frequency of occurrence. 2006, De-Shuang Huang & ‎George William Irwin, Computational Intelligence and Bioinformatics, →ISBN: Ribosomal frameshifting at a particular site can yield two protein products from one coding sequence or one protein product from two overlapping open reading frames.
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