endoxifen

English

endoxifen (uncountable)

A metabolite of tamoxifen, 4-[(Z)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol, that has similar properties
- 2015 July 16, “Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients”, in PLOS ONE‎, DOI:10.1371/journal.pone.0132269:
  It is described as a prodrug since most of its antiestrogen effects are exerted through its hydroxylated metabolites 4-OH-tamoxifen and endoxifen.

单词	endoxifen
释义	endoxifen English Noun endoxifen (uncountable) A metabolite of tamoxifen, 4-[(Z)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol, that has similar properties 2015 July 16, “Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients”, in PLOS ONE‎, DOI:10.1371/journal.pone.0132269: It is described as a prodrug since most of its antiestrogen effects are exerted through its hydroxylated metabolites 4-OH-tamoxifen and endoxifen.
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