dolaphenine
English
Noun
dolaphenine (uncountable)
- (organic chemistry) The compound 2-phenyl-1-(2-thiazolyl)ethylamine normally found associated with a dolastatin
- 2015 July 11, “Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy”, in PLOS ONE, DOI: :
- We subsequently identified the degradation by mass spectrometry as a loss of 186 Da, which is consistent with the hydrolytic cleavage of the C-terminal dolaphenine residue of MMAD (Fig 2a and 2b, Figs a and b in S1 Fig ).
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