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单词 coordinome
释义

coordinome

English

Noun

coordinome (plural coordinomes)

  1. (music) A form of punched tape reader for a synthesizer
  2. (biochemistry) A DNA sequence that serves to coordinate the expression of two or more genes.
    • 2003, Cancer Research - Volume 63, page 4123:
      Second, only in one pair (cMM17-MM17) the expression levels of most coordinome members were similar in melanocyte and melanoma cultures (Figs. 4 and 5).
    • 2012, Silvia Lorenzi, Matteo Forloni, Loredana Cifaldi, Chiara Antonucci, Arianna Citti, Renata Boldrini, Marco Pezzullo, Aurora Castellano, Vincenzo Russo, Pierre van der Bruggen, Patrizio Giacomini, Franco Locatelli & Doriana Fruci, “IRF1 and NF-kB restore MHC class I-restricted tumor antigen processing and presentation to cytotoxic T cells in aggressive neuroblastoma”, in PLoS One, volume 7, number 10:
      The present results support the original suggestion that MHC-I and APM components act as a coordinome with core and peripheral (gene-specific) control features, and a hierarchy of control steps [41].
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