clobenpropit
English
![](Images/wiktionary/Clobenpropit.svg.png.webp)
The structural form of a clobenpropit molecule.
Noun
clobenpropit (uncountable)
- (biochemistry) A histamine H3 antagonist that has neuroprotective effects via stimulation of GABA release in the brain. Chemical symbol: C14H17ClN4S.
References
- Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P (2007), “The human histamine H3 receptor couples to GIRK channels in Xenopus oocytes”, in Eur. J. Pharmacol., volume 567, issue 3, DOI:, PMID 17537431, pages 206–10
- Dai H, Fu Q, Shen Y, Hu W, Zhang Z, Timmerman H, Leurs R, Chen Z. (2007), “The histamine H3 receptor antagonist clobenpropit enhances GABA release to protect against NMDA-induced excitotoxicity through the cAMP/protein kinase A pathway in cultured cortical neurons.”, in European Journal of Pharmacology, volume 563(1-3), PMID 17350613, pages 117-23